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Epigenetic Mechanisms of Long-term Memory

Epigenetic Mechanisms of Long-term Memory We all know that we are able to store sensory experiences for later recall; in a very real sense, collection of memories acquired during life represents our personal identity. However, the neuroscience of memory formation is still in its infancy. We have, at best, a rudimentary understanding of a few of the many complex processes involved. Most memories last for a few brief moments, and are then lost forever. It was thought that long-term memory formation involved structural changes in neural connections vi [...]  Read more >

So Just What the Hell Is a ‘Nootropic’ Anyway?

So Just What the Hell Is a ‘Nootropic’ Anyway? I bet there are more than a few visitors to the site who have never even heard of the word ‘nootropic’. It probably seems like some ridiculous, made up word, designed to bamboozle and impress at the same time. Kind of like most medical words your doctor uses, haha! Anyway, this article is for those people; the ones who have had no previous exposure to the term or those who just want to re-affirm what they understand of the meaning of the word. Newsflash: ‘Nootropic’ IS a made-up word. But then so are all [...]  Read more >

The Effects of Long-Term Nootropic Use

The Effects of Long-Term Nootropic Use Some users of nootropics seem to feel that like most other supplements, these ‘brain boosters’ should be cycled (periods of use interspersed with regular ‘off’ periods) in order to maintain their long-term effectiveness. However this author disagrees with that philosophy, and I shall explain why. Shouldn’t certain supplements be cycled? Certainly, there are supplements that should be cycled and some of these may fall under the general category of ‘nootropic’, however they are those supplements that conta [...]  Read more >

The ‘Shotgun’ Approach to Poor Supplement Design

The ‘Shotgun’ Approach to Poor Supplement Design The shotgun approach to supplement design involves adding or listing as many different (but still relevant – usually) ingredients in one product as possible, usually at very low doses. The reason why some companies feel the need to do this is simply to convince you, the customer, that their product is superior to the competition. After all, the product with the most ingredients relevant to a desired effect, MUST be the best one, right? Wrong. Why is this a bad thing? Although it may be true that all of [...]  Read more >

Acetylcholine: The Performance Neurotransmitter

Acetylcholine: The Performance Neurotransmitter I’m sure you are familiar with neurotransmitters; they are the little signalling molecules that travel across synapses and trigger a response in the target cell, either a neuron or a motor end plate in skeletal muscle – for the purposes of this discussion, anyway, though they do work in other tissues as well. You probably have heard of acetylcholine (ACh) before, just as you have likely heard of dopamine and serotonin – the other ‘main’ neurotransmitters, besides GABA and glutamate. But did you know that [...]  Read more >
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